Publications

Research articles in peer-reviewed journals:

• Comment on "Stereoselective Degradation Kinetics of Theta-Cypermethrin in Rats".
  W. Bicker, M. Lämmerhofer, W. Lindner
  Environ. Sci. Technol., 2006, 40 (24), 7950-7951.

• Determination of ethyl sulfate - a marker for recent ethanol consumption - in human urine by CE with indirect UV detection.
  F. A. Esteve-Turrillas, W. Bicker, M. Lämmerhofer, T. Keller, W. Lindner
  Electrophoresis, 2006, 27 (23), 4763-4771.

• Stereoselective separations of chiral phosphinic acid pseudodipeptides by CEC using silica monoliths modified with an anion-exchange-type chiral selector.
  B. Preinerstorfer, D. Lubda, A. Mucha, P. Kafarski, W. Lindner, M. Lämmerhofer
  Electrophoresis, 2006, 27 (21), 4312-4320.

• Validated method for the determination of the ethanol consumption markers ethyl glucuronide, ethyl phosphate, and ethyl sulfate in human urine by reversed-phase/weak anion exchange liquid chromatography-tandem mass spectrometry.
  W. Bicker, M. Lämmerhofer, T. Keller, R. Schuhmacher, R. Krska, W. Lindner
  Anal. Chem., 2006, 78 (16), 5884-5892.

• Quinine carbamate chiral stationary phases: Systematic optimization of steric selector-selectand binding increments and enantioselectivity by quantitative structure-enantioselectivity relationship studies.
  M. Lämmerhofer, P. Franco, W. Lindner
  J. Sep. Sci., 2006, 29 (10), 1486-1496.

• Silica-based monolithic columns with mixed-mode reversed-phase/weak anion-exchange selectivity principle for high-performance liquid chromatography.
  R. Nogueira, D. Lubda, A. Leitner, W. Bicker, N. M. Maier, M. Lämmerhofer, W. Lindner
  J. Sep. Sci., 2006, 29 (7), 966-978.

• Monolithic silica-based capillary column with strong chiral cation-exchange type surface modification for enantioselective non-aqueous capillary electrochromatography.
  B. Preinerstorfer, D. Lubda, W. Lindner, M. Lämmerhofer
  J. Chromatogr. A, 2006, 1106 (1-2), 94-105.

• A case study of acute human chlorpyrifos poisoning: Novel aspects on metabolism and toxicokinetics derived from liquid chromatography-tandem mass spectrometry analysis of urine samples.
  W. Bicker, M. Lämmerhofer, D. Genser, H. Kiss, W. Lindner
  Toxicol. Lett., 2005, 159 (3), 235-251.

• Investigations of molecular recognition aspects related to the enantiomer separation of 2-methoxy-2-(1-naphthyl)propionic acid using quinine carbamate as chiral selector: An NMR and FT-IR spectroscopic as well as X-ray crystallographic study.
  K. Akasaka, K. Gyimesi-Forrás, M. Lämmerhofer, T. Fujita, M. Watanabe, N. Harada, W. Lindner
  Chirality, 2005, 17 (9), 544-555.

• Alternative high-performance liquid chromatographic peptide separation and purification concept using a new mixed-mode reversed-phase/weak anion-exchange type stationary phase.
  R. Nogueira, M. Lämmerhofer, W. Lindner
  J. Chromatogr. A, 2005, 1089 (1-2), 158-169.

• Determination of chlorpyrifos metabolites in human urine by reversed-phase/weak anion exchange liquid chromatography-electrospray ionisation-tandem mass spectrometry.
  W. Bicker, M. Lämmerhofer, W. Lindner
  J. Chromatogr. B, 2005, 822 (1-2), 160-169.

• Solid-phase capture and release of arginine peptides by selective tagging and boronate affinity chromatography.
  A. Foettinger, A. Leitner, W. Lindner
  J. Chromatogr. A, 2005, 1079 (1-2), 187-196.

• Polymethacrylate-type monoliths functionalized with chiral amino phosphonic acid-derived strong cation exchange moieties for enantioselective nonaqueous capillary electrochromatography and investigation of the chemical composition of the monolithic polymer.
  B. Preinerstorfer, W. Lindner, M. Lämmerhofer
  Electrophoresis, 2005, 26 (10), 2005-2018.

• Functional probing of arginine residues in proteins using mass spectrometry and an arginine-specific covalent tagging concept.
  A. Leitner, W. Lindner
  Anal. Chem., 2005, 77 (14), 4481-4488.

• Spectrophotometric determination of sulfhydryl concentration on the surface of thiol-modified chromatographic silica particles using 2,2'-dipyridyl disulfide reagent.
  R. Nogueira, M. Lämmerhofer, N. M. Maier, W. Lindner
  Anal. Chim. Acta, 2005, 533 (2), 179-183.

• Effects of an arginine-selective tagging procedure on the fragmentation behavior of peptides studied by electrospray ionization tandem mass spectrometry (ESI-MS/MS).
  A. Leitner, W. Lindner
  Anal. Chim. Acta, 2005, 528 (2), 165-173.

• Direct high-performance liquid chromatographic enantiomer separation of anti-inflammatory planar chiral [2.2]paracyclophane-4-acetic acid.
  M. Lämmerhofer, P. Imming, W. Lindner
  Chromatographia, 2004, 60 (Suppl. 1), S13-S17.

• Development of reactive thiol-modified monolithic capillaries and in-column surface functionalization by radical addition of a chromatographic ligand for capillary electrochromatography.
  B. Preinerstorfer, W. Bicker, W. Lindner, M. Lämmerhofer
  J. Chromatogr. A, 2004, 1044 (1-2), 187-199.

• Separation and on-line distinction of enantiomers: A non-aqueous capillary electrophoresis Fourier transform infrared spectroscopy study.
  P. Hinsmann, L. Arce, P. Svasek, M. Lämmerhofer, B. Lendl
  Appl. Spectrosc., 2004, 58 (6), 662-666.

• Direct high-performance liquid chromatographic method for enantioselective and diastereoselective determination of selected pyrethroic acids.
  W. Bicker, M. Lämmerhofer, W. Lindner
  J. Chromatogr. A, 2004, 1035 (1), 37-46.

• Novel enantioselective strong cation exchangers based on sulfodipeptide selectors: Evaluation for enantiomer separation of chiral bases by nonaqueous capillary electrochromatography.
  D. Hebenstreit, W. Bicker, M. Lämmerhofer, W. Lindner
  Electrophoresis, 2004, 25 (2), 277-289.

• HPLC enantiomer separation of a chiral 1,4-dihydropyridine monocarboxylic acid.
  M. Lämmerhofer, O. Gyllenhaal, W. Lindner
  J. Pharm. Biomed. Anal., 2004, 35 (2), 259-266.

• Characterization of a chiral stationary phase by HR/MAS NMR spectroscopy and investigation of enantioselective interaction with chiral ligates by transferred NOE.
  C. Hellriegel, U. Skogsberg, K. Albert, M. Lämmerhofer, N. M. Maier, W. Lindner
  J. Am. Chem. Soc., 2004, 126 (12), 3809-3816.

• Structure-enantioselectivity relationships for the study of chiral recognition in peptide enantiomer separation on cinchona alkaloid-based chiral stationary phases by HPLC: Influence of the N-terminal protecting group.
  C. Czerwenka, M. Lämmerhofer, W. Lindner
  J. Sep. Sci., 2003, 26 (17), 1499-1508.

• Probing of arginine residues in peptides and proteins using selective tagging and electrospray ionization mass spectrometry.
  A. Leitner, W. Lindner
  J. Mass Spectrom., 2003, 38 (8), 891-899.

• High-performance liquid chromatographic enantiomer separation and determination of absolute configurations of phosphinic acid analogues of dipeptides and their α-aminophosphinic acid precursors.
  M. Lämmerhofer, D. Hebenstreit, E. Gavioli, W. Lindner, A. Mucha, P. Kafarski, P. Wieczorek
  Tetrahedron Asymm., 2003, 14 (17), 2557-2565.

• Enantiomeric impurity profiling in ephedrine samples by enantioselective capillary electrochromatography.
  W. Bicker, D. Hebenstreit, M. Lämmerhofer, W. Lindner
  Electrophoresis, 2003, 24 (15), 2532-2542.

• Enantioselective strong cation-exchange molecular recognition materials: Design of novel chiral stationary phases and their application for enantioseparation of chiral bases by nonaqueous capillary electrochromatography.
  S. Constantin, W. Bicker, E. Zarbl, M. Lämmerhofer, W. Lindner
  Electrophoresis, 2003, 24 (10), 1668-1679.

• Micro-HPLC and standard-size HPLC for the separation of peptide stereoisomers employing an ion-exchange principle.
  C. Czerwenka, M. Lämmerhofer, W. Lindner
  J. Pharmaceut. Biomed. Anal., 2003, 30 (6), 1789-1800.
  

• Strong versus weak chiral cation exchangers: comparative evaluation for enantiomer separation of chiral bases by non-aqueous CEC.
  E. Zarbl, M. Lämmerhofer, A. Woschek, F. Hammerschmidt, C. Parenti, G. Cannazza, W. Lindner
  J. Sep. Sci., 2002, 25 (15-17), 1269-1283.

Review articles in peer-reviewed journals:

• Chirally-functionalized monolithic materials for stereoselective capillary electrochromatography.
  M. Lämmerhofer
  Anal. Bioanal. Chem., 2005, 382 (4), 873-877.

• Chiral separations by capillary electromigration techniques in nonaqueous media. II. Enantioselective nonaqueous capillary electrochromatography.
  M. Lämmerhofer
  J. Chromatogr. A, 2005, 1068 (1), 31-57.

• Chiral separations by capillary electromigration techniques in nonaqueous media. I. Enantioselective nonaqueous capillary electrophoresis.
  M. Lämmerhofer
  J. Chromatogr. A,2005, 1068 (1), 3-30.

• Current chemical tagging strategies for proteome analysis by mass spectrometry.
  A. Leitner, W. Lindner
  J. Chromatogr. B, 2004, 813 (1-2), 1-26.

Non-peer-reviewed articles:

• Editorial: Chromatographic chiral separations.
  S. Fanali, M. Lämmerhofer
  J. Sep. Sci., 2006, 29, 1303-1304.

• "Mixed-mode" Reversed-phase/Ionenaustauscher für die Peptidtrennung und -reinigung.
  M. Lämmerhofer, R. Nogueira, W. Lindner
  GIT Spezial Separation, 2006, 26, 10-12.

• Christian Doppler Labor für Molecular Recognition Materials.
  M. Lämmerhofer, W. Lindner
  Nachrichten aus der Chemie, 05/2006 (bzw. Mitteilungsblatt der Gesellschaft Österreichischer Chemiker, 02/2006), 606.

• Gelebte Partnerschaft: Wissenschaft - Wirtschaft.
  W. Lindner
  Nachrichten aus der Chemie, 05/2006 (bzw. Mitteilungsblatt der Gesellschaft Österreichischer Chemiker, 02/2006), 605.

• Replik über Trends und Highlights auf dem "Internationalen Symposium für Hochleistungs-Flüssig-Phasen Trenntechniken - HPLC 2005" in Stockholm.
  M. Lämmerhofer
  Laborzeitschrift GIT, 2005.

• Chirale Anionenaustauscher.
  M. Lämmerhofer, N.M. Maier, W. Lindner
  Nachrichten aus der Chemie, 09/2002.

Book chapters:

• Capillary electrochromatography.
  M. Lämmerhofer, W. Lindner
  in Monolithic materials: Preparation, properties, and applications (F. Svec, T. Tennikova and Z. Deyl, Eds.), Journal of Chromatography Library, Volume 67. Elsevier, Amsterdam, 2003.

• Chiral separations by CE using cinchona alkaloid derivatives as chiral counter-ions.
  M. Lämmerhofer, W. Lindner
  in Methods in Biotechnology, "Chiral separations - Methods and Protocols" (G. Gübitz and M. Schmid, Eds.), The Humana Press, Totowa, NJ, 2002.

Diploma theses:

• Dieter Hebenstreit: Development of novel strong cation exchangers for enantioseparation of chiral bases by capillary electrochromatography (2003).

• Alexandra Föttinger: Development of a selective separation method directed towards arginine/guanidine in combination with liquid chromatography/mass spectrometry (2003).

• Wolfgang Bicker: Stereoselective capillary electrochromatography: Development of novel chiral stationary phases and their application for enantiomeric impurity profiling (2002).

Ph.D. theses:

• Beatrix Preinerstorfer: Novel organic and inorganic monolithic materials for microscale separation techniques (2006).

• Wolfgang Bicker: Analytical solutions to challenging problems in toxicology employing liquid phase separation concepts and mass spectrometry (2006).

• Raquel Nogueira: Development of alternative high-performance liquid chromatographic peptide purification concepts and mixed-mode reversed-phase/ion-exchange type adsorption materials (2005).

• Alexander Leitner: Development and applications of novel recognition concepts for arginine residues in peptides and proteins using mass spectrometry (2003).

• Elfriede Zarbl: Development and optimization of enantioselective separation systems for analysis of ionic compounds by HPLC, CE and CEC (2002).

Habilitation:

• Michael Lämmerhofer: Stereoselective capillary separation systems: Contributions with focus on analysis of pharmaceuticals by electrokinetic techniques (2002).

Patent applications:

• Mixed-modal anion exchange materials
  EP 04 028 798.9 (application date 2004/12/04).

• Method and kit for isolating guanidine or amidine containing compounds
  EP 04 015 869.3 (application date 2004/07/06).

© 2006 Christian-Dopper-Laboratory for Molecular Recognition Materials
Last update: 2006/12/18