Research
The CD-Laboratory for Molecular Recognition Materials is currently addressing the following research topics:
- glycoprotein and glycopeptide separation and analysis (glycomics)
- bioanalytics using dedicated sample preparation materials and protocols, multidimensional analysis concepts and LC-MS/MS
- stereoselective analysis in drug products and biological fluids, the design of chiral stationary phases for analytical and preparative enantiomer separation, and other aspects of chiral drug development
- development of functionalized monolithic separation materials in analytical and preparative column formats for high-performance liquid chromatography (HPLC) and capillary column formats for nano-HPLC and capillary electrochromatography (CEC)
- peptide research focusing on the development of complementary separation concepts and materials with intelligent and more flexible selectivity principles and/or having enhanced loading capacities for peparative applications in order to improve productivities of peptide purification concepts, as well as on the analysis of peptide drug products including stability testing and impurity identification
- biochromatography with focus on the design of materials with advanced properties for biopharmaceuticals' purification and production, specifically for purification of glycoproteins and antibodies produced by biotechnological processes
The combined strong and broad expertise of the CDL for MRM that is contributed by our various committed co-workers covers a wide range of chemical technologies and includes in particular:
- molecular recognition and supramolecular chemistry
- stereochemistry
- separation science and separation technologies from nano-scale to preparative scale, in particular chromatographic and electrokinetic separation methods
- mass spectrometry (MS) and its hyphenation with separation techniques
- analytical method development
- biochromatographic method development
- organic synthesis
- materials science and polymer chemistry related to separation science
In short, the Christian-Doppler-Laboratory for Molecular Recognition Materials performs interdisciplinary research, combining a lot of synthetic work with instrumental analysis!
