Martin-Luther-University Halle-Wittenberg

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Martin-Luther-University Halle-Wittenberg

Martin-Luther-University Halle-Wittenberg
Universitätsplatz 7
06120 Halle/Saale
Germany
www.uni-halle.de

The Department of Pharmaceutical Chemistry which is headed by Prof. Wolfgang Sippl, consist of five working groups focussed on in silico drug design, drug synthesis, and analytics. In the individual working groups, 15 researchers, 26 PhD students and 15 assistants are working on pharmaceutically relevant drug targets, such as nuclear hormone receptors, anti-inflammatory targets, and histone modifying enzymes. A major focus lies on the in silico analysis of proteindrug interaction and understanding biological effects. The chemical laboratories contain all necessary equipment for drug synthesis, testing and analytics whereas the drug design group has all necessary resources (hardware and software) for chemoinformatics and computational chemistry. Teaching of of about 600 pharmacy students is carried out on all aspects of pharmaceutical and medicinal chemistry including basic principles of silico drug development.

Key staff involved
Prof. Dr. Wolfgang Sippl	Professor for Medicinal Chemisty and Head of the Department of Pharmaceutical Chemistry. He has as strong background on computer-assisted drug design, including docking, virtual screening, molecular dynamics studies on pharmaceutically relevant targets. He is involved in many international research programs with academic and industrial groups. He is the co-author of one of the student text books on molecular modeling used in education all over the world. He is responsible for all teaching aspects in Medicinal Chemistry and Drug Design at the Department of Pharm. Chemistry.
Dr. Matthias Schmidt	Pharmacist, senior researcher in the Medicinal Chemistry group. He has a strong background on drug synthesis (multi drug resistance modulators, glycolipids, kinase inhibitors) and analytics. He is involved in the teaching of pharmaceutical chemistry and analytics for pharmacy students and organizes practical courses in pharmaceutical chemistry. He is responsible for two PhD students, working on the tructure-based development of kinase inhibitors.
Dipl.-Pharm. Ralf Heinke	Pharmacist, PhD student in the Medicinal Chemistry group. He is working on the in silico based development of novel inhibitors for epigenetic targets. He has a strong skill in programming and computational chemistry.