Tuesday, 10th of July, 8.30 – 14.00 – Lecture Hall to be announced
Unless Workshops attendants are registered for the FEBS2007 Congress, they will have to pay a one-day registration pass available onsite at the regular registration booths.
The formulation of quantitative models of normal and dysfunctional biological systems helps to provide the basis for a disease-driven drug development process, which can lead to biologically designed medicines. The satellite meeting will discuss how the application of computer simulations to a number of concrete problems can accelerate drug discovery, and can contribute towards the formulation of standards for the use of simulation models in the drug development process. We will discuss how current advances in bioinformatics/computational biology, networking of experts from academia and industry, and growing support from public funders could be used to benefit the drug research and development process. The meeting will include presentations from academic and industry experts in biosimulations, followed by informal discussions.
- Karl Kuchler (Medical University of Vienna, Max F. Perutz Laboratories) Welcome Address
- Igor Goryanin (Edinburgh Centre for Bioinformatics) From Systems Biology to Systems Pathology
- Erik Mosekilde (BioSim) Complex Phenomena in Living Systems
- Galina Lebedeva (Biosystems Informatics Institute, Newcastle) Modelling of NSAIDs Action on Target and Development of Safer Drugs
- Philippe Sanseau (GSK) Biosimulations: Experinces from Drug Discovery
- Alexander Panfilov (University of Utrecht) Anatomically Accurate Modelling in Electrophysiology
- Oleg Demin (Institute for Systems Biology, SPb) Modeling and Informatics for Pharma Industry: Collaborative Opportunities in Russia
- Adriano Henney (AstraZeneca) Title to be confirmed
- David Harrison (Cancer Research Centre, Edinburgh) Systems Oncology
Edinburgh Centre for Bioinformatics (ECB) draws on several highly-rated academic Schools within the University of Edinburgh, on other Universities, and on world-leading biological and biomedical Research Institutes in and around Edinburgh. The ECB provides support to ground level initiatives in the Bioinformatics and Systems Biology fields, integrates teaching-related activities across the University of Edinburgh groups, and identifies leads to several high profile programmes. The centre also provides databases and software tools, and is leading on flagship projects such as the Edinburgh Pathway Editor. Main research themes within the ECB include: human networks reconstruction, annotation, graphical representation and modelling; genome scale in-silico models; neuroinformatics; gene-expression databases; machine learning and web services workflows for bioinformatics and development of infrastructure for visual creation, annotation, analysis and modelling of large scale biological networks.
BioSim is a Network of Excellence established by the European Commission under its 6th Framework Programme. The remit of BioSim is to demonstrate how the use of modern simulation technique can lead to a deeper and more qualitative understanding of the underlying biological, pathological and pharmacological processes, with a view to a more rational drug development process, improved treatment procedures, and a reduction in the needs for animal experiments. Main areas of BioSim research activities are focused on modelling cancer, diabetes, CNS, liver, kidney and heart physiological processes in health and disease.
Scottish Bioinformatics Forum (SBF) is part of a Scottish development initiative funded by the Scottish Government’s education funding (SFC) and economic development agencies (SE). The SBF works together with Scottish Development International, industry organisations, and networking organisations to increase the profile of Scottish Bioinformatics, attract investment in life science research, and to encourage academic excellence in bioinformatics. SBF functions include facilitating multi-centre collaborations, industry and academic joint ventures, partnering, knowledge transfer, and bioinformatics training. As such we perform an important role in promoting bioinformatics as a key enabling technology in Life Science research and development. The SBF provides a comprehensive resource on bioinformatics related expertise, research and activities. We support both the academic research base and commercial organisations by actively promoting training and knowledge transfer of bioinformatics skills. The SBF runs training workshops, seminars and conferences on topics related to bioinformatics.