FRIEDRICH PROPST, Ph.D.
phone     +43-1-4277 52858
Fax         +43-1-4277 52854
E-mail:    friedrich.propst@univie.ac.at

Molecular and functional analysis of microtubule-associated
proteins during differentiation in cell culture and knockout mice


Recent publications (1997-2005)

Propst, F. (1997). Physiology and pathobiochemistry of the cytoskeleton. In: Biologie Prospective, 9e Colloque International de Pont à Mousson (Galteau MM, Henny J, Siest G and Delwaide P, eds), John Libbey, Montrouge, France.

Andrä, K., Lassmann, H., Bittner, R., Shorny, S., Fässler, R., Propst, F., and Wiche, G. (1997). Targeted inactivation of plectin reveals essential function in maintaining the integrity of skin, muscle, and heart cytoarchitecture. Genes & Dev. 11, 3143-3156.

Rhodes, N., Innes, C. L., Propst, F., and Paules, R. S. (1997). Serum starved v-mos-transformed cells are unable to appropriately downregulate cyclins and CDKs. Oncogene 14, 3017-27.

Tögel, M., Wiche, G., and Propst, F. (1998). Evidence against structural and functional identity of microtubule-associated protein MAP1B and proteoglycan claustrin. FEBS Lett. 423, 254-258.

Tögel, M., Wiche, G., and Propst, F. (1998). Novel features of the light chain of microtubule-associated protein MAP1B: microtubule stabilization, self interaction, actin filament binding, and regulation by the heavy chain. J. Cell Biol. 143, 695-707.

Kutschera, W., Zauner, W., Wiche, G., and Propst, F. (1998). The mouse and rat MAP1B genes: genomic organization and alternative transcription. Genomics 49, 430-436.

Linhartova, I., Repitz, M., Draber, P., Nemec, M., Wiche, G., and Propst, F. (1999). Conserved domains and lack of evidence for polyglutamine length polymorphism in the chicken homolog of the Machado-Joseph disease gene product ataxin-3. Biochim. Biophys. Acta 1444, 299-305.

Meixner, A., Wiche, G., and Propst, F. (1999). Analysis of the mouse MAP1B gene identifies a highly conserved 4.3 kb 3' untranslated region and provides evidence against the proposed structure of DBI-1 cDNA. Biochim. Biophys. Acta 1445, 345-350.

Tögel, M., Eichinger, R., Wiche, G., and Propst, F. (1999). A 45-amino acid residue domain necessary and sufficient for proteolytic cleavage of the MAP1B polyprotein precursor. FEBS Lett. 451, 15-18.

Meixner, A., Haverkamp, S., Wässle, H., Führer, S., Thalhammer, J., Kropf, N., Bittner, R.E., Lassmann, H., Wiche, G., and Propst, F. (2000). MAP1B is required for axon guidance and is involved in the development of the central and peripherous nervous system. J. Cell Biol. 151, 1169-1178.

Noiges, R., Eichinger, R., Kutschera, W., Fischer, I., Németh, Z., Wiche, G., and Propst, F. (2002). MAP1A and MAP1B: light chains determine distinct functional properties. J. Neurosci. 22, 2106-2114.

Stroißnigg, H., Repitz, M., Miloloza, A., Linhartová, I., Beug, H., Wiche, G., and Propst, F. (2002). FIP-2, an IKKg-related protein, is associated with the Golgi apparatus and translocates to the marginal band during chicken erythroblast differentiation. Exp. Cell Res. 278, 133-45.

Opal P, Garcia JJ, Propst F, Matilla A, Orr HT, Zoghbi HY. (2003). Mapmodulin/leucine-rich acidic nuclear protein binds the light chain of microtubule-associated protein 1B and modulates neuritogenesis.J. Biol. Chem. 278, 34691-34699. Epub 2003 Jun 14.

Bouquet C, Soares S, von Boxberg Y, Ravaille-Veron M, Propst F, Nothias F. (2004). Microtubule-associated protein 1B controls directionality of growth cone migration and axonal branching in regeneration of adult dorsal root ganglia neurons. J. Neurosci. 24, 7204-7213.

Maurer MH, Grunewald S, Gassler N, Rossner M, Propst F, Wurz R, Weber D, Kuner T, Kuschinsky W, Schneider A. (2004). Cloning of a novel neuronally expressed orphan G-protein-coupled receptor which is up-regulated by erythropoietin, interacts with microtubule-associated protein 1b and colocalizes with the 5-hydroxytryptamine 2a receptor. J. Neurochem. 91, 1007-1017.

Orban-Nemeth Z, Simader H, Badurek S, Trancikova A, Propst F. (2005). Microtubule-associated protein 1S, a short and ubiquitously expressed member of the microtubule-associated protein 1 family. J. Biol. Chem. 280, 2257-2265. Epub 2004 Nov 4.

Back to Propst research interests        Department of Molecular Cell Biology