ProfMagDrValenta

a.o. Univ. Prof. Mag. Dr.
Claudia Valenta

Professor

University of Vienna,
Faculty of Life Sciences
Department of Pharmaceutical Technology and Biopharmaceutics

Althanstrasse 14,
A-1090 Vienna, Austria

room 2E 204

fax +43 (0)1 4277 9554
tel +43 (0)1 4277 55410

email:
claudia.valenta@univie.ac.at

Research focus

Topical drug delivery systems:

  • Improvement of penetration and permeation of drugs through skin
  • Developing and testing of polymers and modified polymers as matrix  for drug topical delivery systems
  • Liposomes, nanoemulsions, microemulsions, cubic phases, multiple emulsions
  • bioavailability of dermal formulations

Teaching

  • Grundlagen der magistralen Arzneimittelherstellung (Vorlesung, 2 Std.) –
    Introduction to practical course on magistral formulae (lecture, 2 h)

  • Magistrale Arzneimittelherstellung (Praktikum, 6 Std.) –
    Practical course on magistral formulae (lab course, 6 h)

  • Grundpraktikum aus Pharmazeutischer Technologie (Praktikum, 1 Std.) –
    Basic practical course on Pharmaceutical Technology (lab course, 1 h)

  • Dermatika und Kosmetika (Vorlesung, 1 Std.) –
    Dermatics and cosmetics (lecture, 1 h)

  • Kosmetik und Naturkosmetik – Bestimmungen in der EU (Vorlesung, 1 Std.) –
    Cosmetics – natural cosmetics (lecture, 1 h)

  • Kosmetik-Übungen (Praktikum, 1 Std.) –
    Practical course for production of cosmetics (lab course, 1 h)

  • Fortgeschrittenenpraktikum aus Pharmazeutischer Technologie (Praktikum, 10 Std.) -
    Advanced course in Pharmaceutical Technology (lab course, 10 h)

  • Seminar zur biopharmazeutischen Forschung (Seminar, 2 Std.) –
    Biopharmaceutical research (seminar, 2 h)

  • Seminar zur pharmazeutisch-technologischen Entwicklung (Seminar, 3 Std.) –
    Recent developments in Pharmaceutical Technology (seminar, 3 h)

 

Selected publications

B.G. Auner, C. Valenta, J. Hadgraft, Influence of phloretin and 6-ketocholestanol on the skin permeation of sodium fluorescein, J. Contr. Rel. 89 (2003) 321-328.

C. Valenta, K. Schultz, Influence of carrageenan on the rheology and skin permeation of microemulsion formulations, J. Contr. Rel. 95 (2004) 257-265.

H. Kählig, C. Valenta, U. Dampfhart, B.G. Auner, Rheology and NMR self diffusion experiments as well as skin permeation of diclofenac-sodium and cyproterone acetate of new gel preparations, J. Pharm.Sci. 94 (2005) 288-296.

C. Valenta, B.G. Auner, I. Loibl, Skin permeation and stability studies of 5-aminolevulinic acid in a new gel and patch formulation, J. Contr. Rel. 107 (2005) 495-501.

Victoria Klang, Julia Schwarz, Barbara Lenobel, Martina Nadj, Josef Auböck, Michael Wolzt, Claudia Valenta (2012) In vitro versus in vivo tape stripping: validation of the porcine ear model and penetration assessment of novel sucrose stearate emulsions, Eur.J.Pharm.Biopharm. 80, 604-614.

Julia C. Schwarz, Elisabeth Pagitsch, Claudia Valenta, Comparison of ATR-FTIR spectra of porcine vaginal and buccal mucosa with ear skin and penetration analysis of drug and vehicle component into pig ear, special issue Eur.J.Pharm.Sci. DOI information:10.1016/j.ejps.2012.12.020

 

B. Biruss, C. Valenta, Skin permeation of different steroid-hormones in polymeric coated liposomal formulations, Eur. J. Pharm. Biopharm. 62 (2006) 210-219.

B. Biruss, H. Kählig, C. Valenta, Evaluation of an eucalyptus-oil containing topical drug delivery system for selected steroid hormones, Int. J. Pharm. 328 (2007) 142-151.

S. Höller, C. Valenta, Effect of selected fluorinated drugs in a “ringing” gel on rheological behaviour and skin permeation, Eur. J. Pharm. Biopharm. 66 (2007) 120-126.

Victoria Klang, Julia C.Schwarz, Silvia Haberfeld, Perry Xiao, Michael Wirth, Claudia Valenta, (2013) Skin integrity testing and monitoring of in vitro tape stripping by capacitance-based sensor imaging,  Skin Research and Technology 19 (1), e259-72