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Welcome to the eLerning platform of the Department of Pharmacology and Toxicology. Our course is part of the teaching program in “General Pharmacology”. It illustrates the principles of receptor functon, pharmacokinetics and how ion channels work.

We combine traditional teaching (lectures, tutorials, laboratory classes) with eLearning (illustrations, self-testing and games).

The course was developed by Eugen Timin, Stanislav Beyl (Flash design) and Steffen Hering. Please send us your suggestions.

1. Pharmacodynamics
1.1 Law of mass action
1.2 Dose response curve
1.3 Dose response curve (task)
1.4 Competetive antagonism
1.5 Competetive antagonism (dose response curves)
1.6 Non-competetive antagonism
1.7 Efficacy
1.8 Full agonist in the presence of partial agonist
1.9 Partial agonist in the presence of full agonist
1.10 Interaction of drugs (task)
1.11 Beta-blocker (task)
1.12 Receptor down regulation
1.13 Spare receptors
 
 
2. Pharmacokinetics
2.1a Single compartment model
2.1b Single compartment model II
2.2 First-pass (presystemic) metabolism
2.3 Two compartment model
2.4 Continuous infusion
 
2.6 Multiple drug administration
2.7 Intravenous & oral administration
2.8 Intravenous & oral administration (task)
2.9 Enzyme induction
2.10 Interruption of drug administration
2.11 Therapeutic range of drug action
2.12 Beta-Phase
 
 
3. Ion channel simulations
3.1 Use-dependent ion channel block
3.2 Calcium channel gating
3.3 HERG channel gating
3.4 HERG channel gating II
   
 
4. Basic knowlege for pharmacologists
4.1 Ligand-gated channel I
4.2 Ligand-gated channel II
4.3 Ligand-gated channel III
4.4 NMDA channel  
4.5 Voltage-gated channel block
     

If you have any problems read REQUIREMENTS or contact us.

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