Welcome to the eLerning platform of the Department of Pharmacology and Toxicology. Our course is part of the teaching program in “General Pharmacology”. It illustrates the principles of receptor functon, pharmacokinetics and how ion channels work.

We combine traditional teaching (lectures, tutorials, laboratory classes) with eLearning (illustrations, self-testing and games).

The course was developed by Eugen Timin, Stanislav Beyl (Flash design) and Steffen Hering. Please send us your suggestions.

1.	Pharmakodynamik
	1.1 Massenwirkungsgesetz
	1.2 Dosis-Wirkungs-Beziehung
	1.3 Aufgabe zur Dosis-Wirkungs-Beziehung
	1.4 Kompetetiver Antagonismus
	1.5 Dosis-Wirkungs-Beziehung bei kompetetivem Antagonismus
	1.6 Nicht kompetetiver Antagonismus
	1.7 Wirksamkeit (Efficacy)
	1.8 Voller Agonist in Anwesenheit eines partiellen Agonisten
	1.9 Partieller Agonist in Anwesenheit eines vollen Agonisten
	1.10 Übungaufgabe (Interaction of drugs)
	1.11 Übungaufgabe ( Beta-blocker)
	1.12 Receptor down regulation
	1.13 Reserve Rezeptoren
2.	Pharmakokinetik
	2.1 Einkompartiment-Modell
	2.2 First-Pass-Effekt
	2.3 Zweikompartiment-Modell
	2.4 Kontinuierliche Infusion
	2.5 Aufgabe zur kontinuierliche Infusion
	2.6 Wiederholte Applikation von Arzneistoffen
	2.7 Intravenöse und perorale Verabreichung
	2.8 Übungsaufgabe (intravenöse und perorale Verabreichung)
	2.9 Enzyminduktion
	2.10 Unterbrechen der Arzneistoff-Gabe/ Auslassen einer Dosis
	2.11 Therapeutische Breite der Arzneimittelwirkung
	2.12 ß-Phase der Arzneistoff-Elimination
3.	Ion channel simulations
	3.1 Use-dependent ion channel block
	3.2 Calcium channel gating
	3.3 HERG channel gating
	3.4 HERG channel gating II
4.	Basic knowlege for pharmacologists
	4.1 Ligand-gated channel I
	4.2 Ligand-gated channel II
	4.3 Ligand-gated channel III
	4.4 NMDA channel
	4.5 Voltage-gated channel block

If you have any problems read REQUIREMENTS or contact us.

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