ao.Prof.Dr. Rosa Lemmens-Gruber

E-mail: rosa.lemmens@univie.ac.at
Phone: +43 1 4277 55325
Fax: +43 1 4277 9553

Address:
Department of Pharmacology and Toxicology
University of Vienna
Althanstrasse 14, 2D 257
A-1090 Vienna, Austria


Selected publications

    2014
  • Calpain-mediated integrin deregulation as novel mode of action for the anticancer gallium compound KP46. Jungwirth U, Gojo J, Tuder T, Walko G, Holcmann M, Schöfl T, Nowikovsky K, Wilfinger N, Schoonhoven S, Kowol CR, Lemmens-Gruber R, Heffeter P, Keppler BK, Berge_r W. Mol Cancer Ther. 2014 Jul 31. read more >>
  • A Novel TNF-mediated Mechanism of Direct Epithelial Sodium Channel Activation. Czikora I, Alli A, Bao HF, Kaftan D, Sridhar S, Apell HJ, Gorshkov B, White R, Zimmermann A, Wendel A, Pauly-Evers M, Hamacher J, Garcia-Gabay I, Fischer B, Verin A, Bagi Z, Pittet JF, Shabbir W, Lemmens-Gruber R, Chakraborty T, Lazrak A, Matthay MA, Eaton DC, Lucas R. Am J Respir Crit Care Med, 2014 Jul 16 read more >>
    2013
  • Mechanism of action of novel lung oedema therapeutic AP301 by activation of ENaC. Shabbir W, Scherbaum-Hazemi P, Tzotzos S, Fischer B, Fischer H, Pietschmann H, Lucas R, Lemmens-Gruber R. Mol Pharm. 84:899-910, 2013 read more >>
  • Sex-Specific-differences in cardiometabolic risk in Type-1-Diabetes. Kautzky-Willer A, Stich K, Hintersteiner J, Kautzky A, Kamyar MR, Saukel J, Johnson BJ, Lemmens-Gruber R. Cardiovasc Diabetol. 12:78, 2013 read more >>
  • Destruxins: fungal-derived cyclohexadepsipeptides with multifaceted anticancer and antiangiogenic activities. Dornetshuber R, Heffeter P, Mohr T, Hazemi P, Seger C, Berge_r W, Lemmens-Gruber R. Biochem Pharmacol 86:361-77, 2013 read more >>
  • AP301, a synthetic peptide mimicking the lectin-like domain of TNF-α, enhances amiloride-sensitive Na+ current in primary dog, pig and rat alveolar type II cells. Tzotzos S, Fischer B, Fischer H, Pietschmann H, Lucas R, Dupré G, Lemmens-Gruber R, Prymaka V, Hazemi P, Shabbir W. Pulm Pharmacol Ther. 26:356-63, 2013 read more >>
    2011
  • Voltage-gated sodium channels: mutations, channelopathies and targets. Andavan GS, Lemmens-Gruber R. Curr Med Chem. read more >>
    2010
  • Essential structural features of TNF-α lectin-like domain derived peptides for activation of amiloride-sensitive sodium current in A549 cells. Hazemi P, Tzotzos SJ, Fischer B, Andavan GS, Fischer H, Pietschmann H, Lucas R, Lemmens-Gruber R. J Med Chem. read more >>
  • Evidence-based intravenous pain treatment with analgesic infusion regimens. Nemec K, Cihal P, Timin E, Kamyar MR, Lemmens-Gruber R. Arzneimittelforschung. read more >>
  • Evaluation of risk factor management of patients treated on an internal nephrology ward: a pilot study. Stemer G, Zehetmayer S, Lemmens-Gruber R. BMC Clin Pharmacol. read more >>
  • Clinical pharmacy services and solid organ transplantation: a literature review. Stemer G, Lemmens-Gruber R. Pharm World Sci. read more >>
  • Cyclodepsipeptides from marine sponges: natural agents for drug research. Andavan GS, Lemmens-Gruber R. Mar Drugs read more >>
    2009
  • Cyclodepsipeptides - potential drugs and lead compounds in the drug development process. Lemmens-Gruber R, Kamyar MR, Dornetshuber R. Curr Med Chem. read more >>
  • Effects of the anthelmintic drug PF1022A on mammalian tissue and cells. Dornetshuber R, Kamyar MR, Rawnduzi P, Baburin I, Kouri K, Pilz E, Hornbogen T, Zocher R, Berge_r W, Lemmens-Gruber R. Biochem Pharmacol. read more >>
  • Oxidative stress and DNA interactions are not involved in Enniatin- and Beauvericin-mediated apoptosis induction. Dornetshuber R, Heffeter P, Lemmens-Gruber R, Elbling L, Marko D, Micksche M, Berge_r W. Mol Nutr Food Res. read more >>
  • Interactions between ABC-transport proteins and the secondary Fusarium metabolites enniatin and beauvericin. Dornetshuber R, Heffeter P, Sulyok M, Schumacher R, Chiba P, Kopp S, Koellensperger G, Micksche M, Lemmens-Gruber R, Berge_r W. Mol Nutr Food Res. read more >>
    2008
  • IFN-beta increases listeriolysin O-induced membrane permeabilization and death of macrophages. Zwaferink H, Stockinger S, Hazemi P, Lemmens-Gruber R, Decker T. J Immunol. read more >>
    2007
  • toxEnniatin exerts p53-dependent cytostatic and p53-independent cytotoxic activities against human cancer cells. Dornetshuber R, Heffeter P, Kamyar MR, Peterbauer T, Berge_r W, Lemmens-Gruber R. Chem Res Toxicol. read more >>
    2006
  • Effects of moniliformin in presence of cyclohexadepsipeptides on isolated mammalian tissue and cells. Kamyar MR, Kouri K, Rawnduzi P, Studenik C, Lemmens-Gruber R. Toxicol In Vitro. read more >>