Publications:
2005:
Khom S, Baburin I, Timin EN, Hohaus A, Sieghart W, Hering S.(2005): Pharmacological properties of GABAA- receptors containing gamma1- subunits. MolPharm.
Hohaus A, Beyl S, Kudrnac M, Berjukow S, Timin EN, Marksteiner R, Maw MA, Hering S. (2005) Structural determinants of L-type channel activation in segment IIS6 revealed by a retinal disorder. J Biol Chem.
Hemara-Wahanui A., Berjukow S., Hope C.I., Dearden P.K., Wu S.-B., Wilson-Wheeler J., Sharp D.M., L.-Treweek P., Clover G.M., Hoda J.-Ch., Striessnig J., Marksteiner R., Hering S. and M.A. Maw (2005) A CACNA1F mutation identified in an X-linked retinal disorder shifts the voltage dependence of Cav1.4 channel activation. Proc Natl Acad Sci U S A . 24;102(21):7553-8.
2004:
Sinnegger-Brauns M.J., Hetzenauer A., Huber I.G., Renstrom E., Wietzorrek G., Berjukov S., Cavalli M., Walter D., Koschak A., Waldschutz R., Hering S., Bova S., Rorsman P., Pongs O., Singewald N. and J. Striessnig (2004) Isoform-specific regulation of mood behavior and pancreatic beta cell and cardiovascular function by L-type Ca 2+ channels. J Clin Invest. 113(10):1430-9.
Strasser H., Berjukow S., Marksteiner R., Margreiter E., Hering S., Bartsch G. and S. Hering (2004) Stem cell therapy for urinary stress incontinence.
Exp Gerontol. 39(9):1259-65. Review.
Strasser H., Marksteiner R., Margreiter E., Pinggera G.-M., Mitterberger M., Fritsch H., Klima G., Radler C., Stadlbauer K.-H., Fussenegger M., Hering S. und G. Bartsch (2004) Stem cell therapy for urinary incontinence Urologe A . 2004 Oct;43(10):1237-41.
Berjukow S., Margreiter E., Marksteiner R., Strasser H., Bartsch G. and S. Hering (2004) Functional properties of single muscle cells of the rhabdosphincter of the male urethra. Prostate. 15; 58(3):238-47.
Ott HC, Berjukow S, Marksteiner R, Margreiter E, Boeck G, Laufer G, Hering S. (2004) On the fate of skeletal myoblasts in a cardiac environment: Down regulation of voltage gated ion channels. J Physiol. 558. 3: 793-805.
Berjukow S., Margreiter E., Marksteiner R., Strasser H., Bartsch G. and S. Hering (2004) Functional properties of single muscle cells of the rhabdosphincter of the male urethra. Prostate. 15; 58(3):238-47.
Kamelger F.S., Marksteiner R., Margreiter E., Klima G., Wechselberger G., Hering S., and H. Piza (2004) A comparative study of three different biomaterials in the engineering of skeletal muscle using a rat animal model. Biomaterials. 25(9): 1649-55.
2002 and earlier:
Hering S (2002) Beta-Subunits: fine tuning of Ca(2+) channel block. Trends Pharmacol Sci. 23:509-13.
Marksteiner R., Schurr P., Berjukow S., Margreiter E., Perez-Reyes E. and S. Hering (2001) Inactivation determinants in segment IIIS6 of Ca v 3.1. J. Physiol. 37: 27-34.
Sokolov S., Timin E.N. and S. Hering (2001) On the role of Ca 2+ - and voltage-dependent inactivation in Ca V 1.2 sensitivity for the phenylalkylamine
(-)gallopamil. Circ Res. 89:700-708.
Berjukow S. and Hering S (2001) Voltage-dependent acceleration of Cav1.2 channel current decay by (+)- and (-)-isradipine. Br. J. Pharmacol. 133: 959-966.
Berjukow S., Marksteiner R., Sokolov S., Weiß R.G., Margreiter E. and S. Hering (2001) Amino acids in segment IVS6 and b -subunit interaction support distinct conformational changes during Ca v 2.1 inactivation . J. Biol. Chem. 276: 17076-82 .
Hering, S., Berjukow S., Sokolov S., Marksteiner R., Weiß R.G., Kraus R. and E.N. Timin (2000) Molecular determinants of inactivation in voltage-gated Ca 2+ channels J. Physiol. 528: 237-249 . (Review)
Berjukow, S., Marksteiner, R., Gapp F., Sinnegger M.J., and S. Hering (2000) Molecular mechanism of calcium channel block by isradipine: Role of a drug-induced inactivated channel conformation. J. Biol. Chem. 275: 22114-22120 .
Sokolov, S., Weiß, R., Timin, E.N., and S. Hering (2000) Modulation of slow inactivation in class A Ca 2+ channels by b -subunits. J. Physiol. 527: 445-454.
Sokolov S., Weiß, R., Kurka, B., Gapp F., and S. Hering (1999) Inactivation determinant in the I-II loop of the Ca 2+ channel a 1 subunit and b -subunit interaction affect sensitivity for the phenylalkylamine (-)gallopamil. J. Physiol. 519: 315-322.
Berjukow, S., Gapp F., Aczel S., Sinnegger M.J., Mitterdorfer J., Glossmann H. and S. Hering (1999) Sequence differences between a 1C and a 1S Ca 2+ channel subunits reveal structural determinants of a guarded and modulated benzothiazepine receptor J. Biol. Chem. 274: 6154-6160.
Mitterdorfer J., Grabner M., Kraus R.L., Hering S., Prinz H., Glossmann H., and J. Striessnig (1998) Molecular basis of drug interaction with L-type Ca 2+ channels. J. Bioenerg. Biomembr. 30: 319-334 (Review)
Hering S., Berjukow S., Aczel S, and E.N. Timin (1998) Calcium channel block and inactivation: common molecular determinants. Trends in Pharmacological Sciences 19: 439 – 443 (Review)
Kraus R. L., Hering S., Grabner M., Ostler D., and J. Striessnig (1998). Molecular mechanism of diltiazem interaction with L-type Ca 2+ channels J. Biol. Chem. 273: 27205-27212.
Aczel, S, Kurka, B., and S. Hering (1998) Mechanism of voltage- and use-dependent block of Ca 2+ channels by mibefradil. Brit. J. Pharmacol. 125: 447 – 454.
Hering S (1998) Small-volume and rapid extracellular solution exchange around Xenopus oocytes during voltage clamp recordings. Pflugers Arch. 436: 303-307.
Kraus R. L., Sinnegger M. J., Glossmann H., Hering S., and J. Striessnig (1998) Familiar hemiplegic migrane mutations change a 1A Ca 2+ channel kinetics. J. Biol. Chem. 273: 5586 – 5590.
Striessnig J., Grabner M., Mitterdorfer J., Hering S., Sinnegger M.J., and H. Glossmann (1998) Structural basis of drug binding to L Ca 2+ channels. Trends in Pharmacological Sciences 19: 108 – 115 (Review)
Hering S , Aczel S, Kraus R., Berjukow S., Striessnig J., and E.N. Timin (1997) Molecular mechanism of calcium channel block by phenylalkylamines: Role of inactivation Proc. Natl. Acad. Sci. USA 94: 13323 – 13328.
Sinnegger M. J., Wang Z., Grabner M., Hering S., Striessnig J., Glossmann H., and J. Mitterdorfer (1997) Nine L-type amino acid residues confer full 1,4-dihydropyridine sensitivity to the neuronal calcium channel a 1A subunit. J. Biol. Chem. 272: 27686 – 27693.
Degtiar V. E., Aczel S., Doring F., Timin E. N., Berjukow S., Kimball D., Mitterdorfer, J., and S. Hering (1997) Calcium channel block by
(-)devapamil is affected by the sequence environment and composition of the phenylalkylamine receptor site. Biophys. J. 73: 157 – 167.
Mitterdorfer J., Wang Z., Sinnegger M.J., Hering S., Striessnig J., Grabner M., and H. Glossmann (1996) Two amino acid residues in the IIIS5 segment of L-type calcium channels differentially contribute to 1,4 dihydropyridine sensitivity. J. Biol. Chem. 271: 30330–30335.
Hering S., Aczel S., Grabner M., Doring F., Berjukow S., Mitterdorfer J., Sinnegger M.J., Striessnig J., Degtiar D.E., Wang Z., and H. Glossmann (1996) Transfer of high sensitivity for benzothiazepines from L-Type to class A (BI) calcium channels. J. Biol. Chem. 271: 24471 – 24471.
Pichler M., Wang Z., Grabner-Weiss C., Reimer D., Hering S., Grabner M., Glossmann H. and J. Striessnig (1996) Block of P/Q-type calcium channels by therapeutic concentrations of aminoglycoside antibiotics. Biochemistry 35: 14695 - 14664.
Berjukow S., Aczel S., Beyer B., Kimball D., Dichtl M., Hering S., and J. Striessnig (1996) Extra- and intracellular action of quaternary devapamil on muscle L-type Ca-channels. Brit. J. Pharmacol. 119: 1197 – 1202.
Berjukow S., Doring F., Froschmayr M., Grabner M., Glossmann H., and S. Hering (1996) Endogenous calcium channels in human embryonic kidney (HEK293) cells. Brit. J. Pharmacol. 118, 748 – 754.
Doring F, Degtiar V.E., Grabner M., Striessnig J., Hering S., and H. Glossmannn (1996) Transfer of L-type calcium channel IVS6 segment increases phenylalkylamine sensitivity of a 1A J. Biol. Chem. 271: 11745 – 11749.
Grabner M, Wang Z, Hering S, Striessnig J, and H. Glossmann (1996) Transfer of 1,4-dihydropyridine sensitivity from L-type to class A (BI) calcium channels. Neuron 16: 207-218.
Browns T., Cai Zhen-Wei., Kimball D., Kang Hee-Chol, Haugland R.P., Berger W., Berjukow S., Hering S., Glossmann H., and J. Striessnig (1995) The benzothiazepinone binding domain of purified L-type calcium channels: direct labeling using a novel fluorescent diltiazem analogue. Biochemistry 34: 3461 – 3469.
Savchenko A., Glossmann, H., and S. Hering (1995) Improved microperfusion chamber for rapid and multiple solution exchange in single adherent cells. Pflugers Arch. 429: 436 – 442.
Wang Z., Grabner M., Berjukow S., Savchenko A., Glossmenn H., and S. Hering (1995) Chimeric L-type Ca channels expressed in Xenopus laevis oocytes reveal role of repeats III and IV in activation gating. J. Physiol. 486: 131 – 137.
Grabner M., Wang Z., Mitterdorfer J., Rosenthal F., Charnet P., Savchenko A., Hering S., Dejian R., Hall L.M., and H. Glossmann (1994) Cloning and functional expression of a neuronal calcium channel ? subunit from house fly ( Musca domestica ) J. Biol. Chem. 269: 23668 – 23674.
Glossmann H., Hering S., Savchenko A., Berger W., Friedrich K., Garcia M.L., Goetz M.A., Liesch J.M., Zink D.L., and G.J. Kaczorowski (1993) A light stabilizer (Tinuvin 770) that elutes from polypropylene plastic tubes is a potent L-type channel blocker Proc. Natl. Acad. Sci. USA 90: 9523-9527 .
Hering S., Savchenko A., Strubing C., Lakitsch M., and J. Striessnig (1993) Extracellular localisation of the benzothiazepine binding domain of L-type calcium channels. Mol. Pharm. 43: 820-826.
Strubing C., Hering S., and H. Glossmann (1993) Evidence for an external localisation of dihydropyridine agonist receptor sites on smooth muscle and skeletal muscle calcium channels. Brit. J. Pharmacol. 108: 884-891.
Hering S., Hughes A., Timin E.N., and T.B. Bolton (1993) Modulation of calcium channels in aretrial smooth muscle cells by dihydropyridine enantiomers. J. Gen. Physiol. 101: 393 – 410.
Timin E. N., S. Hering (1992) Method for estimation of drug affinity constants to the open conformational state of calcium channels . Biophys. J. 63: 808-814.
Knaus H.-G., Striessnig J., Hering S., Marrer S., Schwenner E., Holtje H., and H. Glossmann (1992) [ 35 S] Sadopine, a novel high affinity, high specific activity, L-type calcium channel probe: Characterisation of two equipotent diastereomers with opposite allosteric properties. Molecular Pharmacology 41: 298-307.
Hughes A.D., Hering S., and T.B. Bolton (1990) The action of caffeine on inward barium current through voltage dependent calcium channels in single rabbit ear artery cells Pflugers Arch. 416: 462-466.
Hughes A.D., Hering S., and T.B. Bolton (1990) Evidence that agonist and antagonist enantiomers of the dihydropyridine PN 202-791 act at different sites on the calcium channel of vascular muscle. Brit. J. Pharmacol. 101: 3-5.
Hering S., Kleppisch T., Timin E.N., and R. Bodewei (1989) Characterization of the calcium channel state transitions induced by enantiomers of the 1,4-dihydropyridine SANDOZ 202 791 in neonatale rat heart cells. Pflugers Arch. 414: 690-700.
Hering, S., Bolton,T.B., Beech,D.J., and S.P. Lim (1989) On the mechanism of calcium channel block by D600 in single smooth muscle cells from rabbit ear artery Circ. Res. 64, 928-936.
Hering, S., Beech,D.J., Boton, T.B., and S.P. Lim (1988) Action of nifedipine or BAY K 8644 is dependent on calcium channel state in single smooth muscle cells from rabbit ear artery Pflugers Arch. 411, 590-592.
Schubert, B., Bodewei,R., Hering,S., and A. Wollenberger (1987) Cell-attached patch clamp measurement of macroscopic rapid inward sodium current in cultured heart cell reaggregates J. Mol. Cell. Cardiol. 19: 1129-1139.
Hering, S., Beech,D.J., and T.B. Bolton (1987) Voltage dependence of the actions of nifedipine and BAY K 8644 on barium currents recorded from single smooth muscle cells from the rabbit ear artery. Biomed. Biochim. Acta 46: 657-661.
Hering, S., Beech,D.J., and T.B. Bolton (1987) A simple method of fast extracellular solution exchange for the study of whole-cell or single channel currents using patch-clamp technique Pflugers. Arch. 410: 335-337.
Bodewei, R., Hering,S., Schubert,B., and A. Wollenberger (1987) Inhibition of calcium channels in neuroblastoma x glioma hybrid cells by verapamil, D600, diltiazem and nisoldipine. Biomed. Biochim. Acta 46: 688-690.
Schubert, B., Hering,S., Bodewei,R., and A. Wollenberger (1986) Frequency-dependent (cumulative) blockade of sodium channels in isolated rat myocardial cells by an antiarrhythmic drug ethmozine. Byull. Eksp. Biol. Med. 5: 55-58 .
Schubert, B., Bodewei,R., Hering,S., and A. Wollenberger (1986) A patch clamp study of the action of ethacyzine on the rapid inward sodium current in single rat heart muscle cells. Eur. J. Pharmacol. 126: 309-312.
Schubert, B., Hering,S., Bodewei,R., Rosenshtraukh,L.V., and A. Wollenberger (1986) Use- and voltage-dependent depression by ethmozine (moricizine) of the rapid inward sodium current in single rat ventricular muscle cells. J. Cardiovas. Pharmacol. 8: 358-366.
Bodewei, R., Hering, S., Schubert,B., Winkler,J. and A. Wollenberger (1985) Calcium channel block by phenytoin in neuroblastoma x glioma hybrid cells. Biomed. Biochim. Acta 44: 1229-1237.
Schubert,B., Hering,S., Bodewei,R., Undrovinas,A., and A. Wollenberger (1985) Sodium current measured by a patch clamp technique in cultured heart cell reaggregates from newborn rat ventricles. IRCS Med.Sci. 13, 184-185.
Bodewei,R., Hering,S., Schubert,B., Winkler,J., and A. Wollenberger (1985) Calcium channel block by phenytoin in neuroblastoma x glioma hybrid cells. Biomed. Biochim. Acta 44: 1229-1237.
Hering, S., Bodewei,R., Schubert,B., Krause,E.G., and A. Wollenberger (1985) Trapidil and other 5-triazolo-(1,5-alpha)-pyrimidine derivatives as calcium channel blockers in 108CC5 cells. Biomed. Biochim. Acta . 44: 37-41.
Hering, S., Bodewei,R., Schubert,B., Rohde,K., and A. Wollenberger (1985) A kinetic analysis of the inward calcium current in 108CC15 neuroblastoma x glioma hybrid cells Gen. Physiol. Biophys. 4: 129-141.
Bodewei, R., Hering, S., Schubert,B., and A. Wollenberger (1985) Sodium and calcium currents in neuroblastoma x glioma hybrid cells before and after morphological differentiation by dibutyryl cyclic AMP. Gen. Physiol. Biophys. 4: 113-127.
Hering, S., Bodewei, R., and A. Wollenberger (1983) Sodium current in freshly isolated and in cultured single rat myocardial cells: frequency and voltage-dependent block by mexiletine J. Mol. Cell. Cardiol. 15: 431-444.
Bodewei, R., Hering, S., Lemke,B., Rosenshtraukh,L.V., Undrovinas,A.I., and A. Wollenberger (1982) Characterization of the fast sodium current in isolated rat myocardial cells: simulation of the clamped membrane potential. J. Physiol. 325: 301-315.
Undrovinas, A.I., Yushmanova, A.V., Hering,S., and L.V. Rosenshtraukh (1980) Voltage clamp method on single cardiac cells from adult rat heart. Experientia 36: 572-574.
Undrovinas, A.J., Yushmanova, A.V., Hering,S., and L. V. Rosenstraukh (1979) Use of voltage clamp method in single mammalian cardiac cells for ionic current measurement Physiol. J. USSR. 66: 602-606.
Book chapters
Hering, S, Sokolov, S., Berjukow, S., Marksteiner, R., Margreiter E. and Evgeni N. Timin (2004) Calcium channel block and inactivation: Insights from structure-activity studies in “Voltage gated calcium channels” ed. G. Zamponi Landes Bioscience
Timin E.N., Berjukow S. and S. Hering S (2004) “ Concepts of calcium channel state-dependent pharmacology” in “Calcium channel pharmacology” ed. by Stefan I McDonough Kluwer Academic/Plenum Publisher, New York.
Mitterdorfer J., Hering S., Aczel S., Berjukow S., Degtiar V., Doring F., Grabner M., Kraus R., Sinnegger M.J., Srtriessnig J., Wang Z., Glossmann H. Molecular basis of drug interaction with calcium channels: a constructive approach In Low voltage activated T-type calcium channels ed. by Tsien, Clozel, Nargeot, Adis international, 1998, p. 351-365.
Striessnig, J., Hering, S., Berger, W., Catterall, W.A., and H. Glossmann. Calcium-antagonist binding domains of L-type calcium channels. In Ion channels in the cardiovascular system: Function and Dysfunction. , edited by Brown, A.M., Catterall, W.A., Kaczorowski, G.J., Spooner, P.M., and Strauss, H.C.,Washington,D.C.:AAAS Press, 1994.
Hering S. and Timin E.N. Estimation of drug binding constants to calcium channel conformational states In Molecular and cellular biology of pharmacological targets , p.189-219. eds. Striessnig J., Glossmann H. Plenum Press, New York, 1993.
Bolton T.B., Hering, S., and Aaronson P.I. Voltage-dependent calcium channels of smooth muscle cells in Ion transport p.117-126. Academic Press, 1989. |
