Applying Stein Shrinkage: Theory and Experiment Rudolf Beran University of California, Davis Stein's fundamental insights on shrinkage estimation, initially viewed as a theoretical curiosity, introduced a powerful class of regularization strategies that reduce risk. This talk considers indirect applications of Stein shrinkage to arrays of means in linear models through adaptive penalized least squares and adaptive hypercube estimators. Some limitations of current theory are noted. Numerical experiments bring out real-world considerations that underlie effective practical uses of Stein shrinkage.