Route 66

Chicago IL
Los Angeles CA

Arguably America's most famous highway, Route 66 (now Interstate 40) stretches in a large curve of some 2,500 miles
From Chicago IL to St Louis MO,
to Tulsa OK,

to Oklahoma City,

to Amarillo TX and Tucumcari NM,

to Albuquerque and Gallup NM

to Flagstaff and Kingman AZ
to Barstow CA and, finally, Los Angeles

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Route 66