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Faculty of Life Sciences
Department of Nutritional Sciences
Emerging Field Oxidative Stress and DNA Stability

Althanstraße 14
1090 Vienna

Phone: +43 1 4277-54930
Fax: +43 1 4277-9549

In the Pharmaceutical Centre (Pharmaziezentrum, UZA2)
Level 5, section E, rooms 2E542-2E558


Scientific Symposium at the Department of Nutritional Sciences (24. & 25.Nov. 2011)
The symposium will deal on high level with top issues of current scientific efforts. The first day ...

Research Platform "Active Aging" approved
The Faculties of Life Sciences and Sports Sciences and University Sports of the University of Vien ...

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Research Platform - Active Ageing  

Active Ageing - Improvement of the Health Status, Motor Competence and Quality of Life in the Elderly

Funding Body: University Vienna

Duration: 2011-2014

Principal Investigator:
Karl-Heinz Wagner
Barbara Wessner 

Main Project group:
Bernhard Franzke, PhD student
Anela Tosevska, PhD student
Barbara Halper, PhD student
Stefan Oesen, PhD student

Master/Diploma students
Waltraud Jandrasitz, Diploma student
Heidemarie Peherstorfer, Diploma student
Martina Kellner, Diploma student
Irina Demund, Master student
Irene Redlinghofer, Diploma student
Klemens Johannes Krejci, Diploma student
Carolin Purer, Master student
Cooperation partners:
Dr. Barbara Wessner, Department of Sport Sciences, University of Vienna
Prof. Norbert Bachl, Department of Sport Sciences, University of Vienna                                                              Dr. Joanne Therese Blanchfield, School of Molecular and Microbial Sciences, The University of Queensland, Australia.  
Prof. Jirka Neuzil, School of Medical Science, Griffith University, Australia.
Prof. Verena Dirsch, Department of Pharmacognosy, Molecular Targets, University of Vienna.
Prof. Henrik Poulsen, Department of Clinical Pharmacology, University Hospital, Copenhagen, Denmark.

Short description:
The Faculties of Life Sciences and Sports Sciences and University Sports of the University of Vienna establish a unique interfaculty Research Platform, focusing on research in Health Sciences and Ageing on a cellular and molecular level which should also include educational training of graduate students embedded in a multidisciplinary research cluster. The research platform is based on collaborative research and also on the educational capacity from Nutritional Sciences (Emerging Field Oxidative Stress and DNA Stability), Pharmacy (Pharmacognosy, Molecular Target group), Sports Sciences (Sport and Exercise Physiology) and the Austrian Institute of Sport Medicine (ÖISM). Health and health promotion are major topics of both faculties and represent a central intersection of the present as well as of future research perspectives. The complementary expertise of the consortium members with background in nutritional sciences, pharmacy, sports sciences, exercise physiology and molecular biology and their national and international cooperations enables the establishment of a national unique research platform at the University of Vienna with international linkage. The planned initiative ties in with topics defined in the Development plan (Entwicklungsplan) of the University of Vienna with emphasis on Bioactive Molecules, Biofunctionality of Food, Molecular Nutrition, Drug Discovery from Nature, Sport Physiology as well as Physical Activity in the Elderly. Further co-operations will be possible with the University Focus of Ageing in the Society (which is social science based). The planned research platform will draw the focus on ageing and lifestyle changes thereby elucidating underlying molecular mechanisms and genome stabilizing effects, training-effect relationships and improving the general health and nutritional status. Experiments will focus on skeletal cell lines and lymphocytes isolated from people of different age as well as on a large and long term human intervention study, addressing physical activity and/or nutrition optimization. Lifestyle interventions will be observed comprehensively in muscle, plasma, lymphocytes and urine with sound and strongly accepted biomarker as well as with observational marker such as Quality of Life measurement or depression score, which are state of the art in gerontology. Particularly age related goals will be addressed such as strategies in the prevention and therapy of sarcopenia, the increase of the nutritional status or the fall frequency, which significantly impacts elderly health but also health economy. The major aim of the ActiveAgeing Group is, however, to provide high-level research on ageing and the impact of lifestyle on elderly with molecular and cellular tools. Cooperation partner will guarantee that the results will be translated to public and implemented in official recommendations. High level research and the achievement of aims will be permanently controlled by an international Scientific Advisory Board. Another goal will be the support of the training of master and PhD students, who are working within the platform activities, by carefully selected courses, lab rotations, joint supervision as well as support to attend conferences and for stays abroad. The platform will be lead by Karl-Heinz Wagner. Oliver Neuabauer and other members of the Emerging Field will be responsible for main research activities.

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