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Plant signal transduction and physiology
Strategies of biochemical adaptation to environmental changes
(abiotic or biotic stress, light) or during developmental
switches in plants are the major focuss of our work. These
processes require a strict regulation and coordination of
different cellular activities, for example coordination of
chloroplast- and cellular metabolism. We investigate
signaling pathways, which are involved in the regulation of
these events. Recently, we were able to demonstrate the
essential role of an Arabidopsis MAP kinase cascade for
adaptation to salt- and cold stress (Teige et al. (2004) Mol.
Cell 15, 141-152.
One topic to be addressed in the future is the cross-talk of these signaling pathways with other pathways responding to the same stimuli such as Ca2+-dependent protein kinases, which are activated under similar stress conditions. Therefore, we started to analyse the Ca2+-dependent protein kinase CPK3, which seems to be associated with chloroplasts in Arabidopsis. This kinase is also activated by different abiotic stresses, but molecular targets have not been identified so far.
M. Teige, E. Scheikl, V. Reiser , H. Ruis and G. Ammerer (2001): Rck2, a member of the CaM- protein kinase family links protein synthesis to high osmolarity MAP-kinase signaling in budding yeast. Proc. Natl. Acad. Sci (USA) 98, 5625-5630. (pubmed)
M. Teige, M. Melzer and K.-H. Süss (1998): Purification, Properties, and In situ localization of the Calvin cycle enzymes D-ribulose 5-phosphate 3-epimerase and transketolase from spinach chloroplasts. Eur. J. Biochem. 252, 237-244.
C. Velot, Mark B. Mixon, Markus Teige, and Paul A. Srere (1997): Model of a Quinary Structure between Krebs TCA Cycle Enzymes: A Model for the Metabolon. Biochemistry 36, 14271-14276.
M.Teige, S. Kopriva, H. Bauwe and K.-H. Süss (1996): Primary structure of chloroplast transketolase from potato (Accession No. Z50099). Plant Physiology 112, 1735.
M. Teige, S. Kopriva, H. Bauwe and K.-H. Süss (1995): Chloroplast pentose-5-phosphate 3-epimerase from potato: cloning, cDNA sequence, and tissue-spezific enzyme accumulation. FEBS Letters 377, 349-352.
M. Teige, R. Weidemann and G. Kretzmer (1994): Problems with serum-free production of antithrombin III regarding proteolytic activity and product quality. J. Biotechnol. 34, 101-105.
M. Teige, B. Huchzermeyer and G. Schultz (1990):
Inhibition of Chloroplast ATP-synthase/ ATP-ase Is a Primary
Effect of Heavy Metal Toxicity in Spinach Plants. Biochem.
Physiol. Pflanzen 186, 165-168.
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