Univ.-Prof. Dr. Tilman Grune

picture of Tilman Grune

Professorship of Physiological Chemistry and Cellular Biochemistry at the Faculty of Chemistry

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Curriculum Vitae:

born 1962 in Bad Saarow, Germany
1981-1987 Studies: 'Medical Biochemistry', II. Medical Institute Moscow, Russia
1986-1987 Diploma level: Comparative analysis of structures of cytochrome P-450 isoforms of the liver
1987-1992 Research assistant at the Institute of Biochemistry of the Medical Faculty (Charité), Humboldt University Berlin, Germany
1992 Graduation (MD in Biochemistry): Nucleotide degradation and free radical damage during ischemia and reperfusion of the rat small intestine
1992-1993 Research assistant at the Research Institute of Molecular Pharmacology Berlin, Germany
1993-1994 Post-doctoral fellowship at the Institute of Molecular Biology and Biochemistry, Albany Medical College, Albany NY, USA
1994-2000 Head of the research division of the Clinics of Physical Medicine and Rehabilitation of the Medical Faculty (Charité), Humboldt University Berlin, Germany
1998 Habilitation (Lecturer of Biochemistry): Secondary antioxidative defense systems in mammalian cells – the removal of oxidation products as demonstrated by the degradation of the lipid peroxidation product 4-hydroxynonenal and the removal of oxidatively modified proteins
2000-2003 Head of the Free Radical Research Division of the Neuroscience Research Centre of the Medical Faculty (Charité), Humboldt University Berlin, Germany
2003-2006 Head of the Free Radical Research Laboratory, Research Institute of Environmental Health, Heinrich Heine University Duesseldorf, Germany
2006-2010 Chair of the Department of Biofunctionality and Safety of Food in the Institute of Biological Chemistry and Nutrition, University of Hohenheim, Stuttgart, Germany
2010-2014 Chair of the Department of Nutritional Toxicology in the Institute of Nutrition, Friedrich Schiller University, Jena, Germany
2013 Dr. h.c. University of Buenos Aires
2014 Founding Co-Editor-in-Chief of 'Redox Biology'
since 2014 Scientific Director of the German Institute of Human Nutrition (DIfE) Potsdam-Rehbrücke and Chair of the Department of Molecular Toxicology, DIfE/University of Potsdam, Germany
since May 2020 Professor for Physiological Chemistry and cellular Biochemistry (part-time), Department of Physiological Chemistry, University of Vienna

Research areas:

* Cellular redox biochemistry and antioxidative defense mechanisms
* Protein oxidation and intracellular proteolysis during cellular stress response
* Aging, cellular senescence and functional role of protein aggregates
* Biomarkers of redox-status, nutrition and aging in human cohorts
* Nutritional impact on the aging process